Thymosin Alpha-1 (TA1) 5mg — also known as Thymalfasin — from Peptide Tech is a premium, lyophilized research-use-only (RUO) peptide supplied at ≥99% purity (HPLC & MS verified). This 28-residue, N-terminally acetylated peptide is packaged for rigorous in-vitro work in immunology, cell-signaling, and analytical method development — with full batch traceability and QR-linked COA.
Specifications
| Property | Details |
|---|---|
| CAS Number | 62304-98-7 |
| Chemical Name | Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH (Thymosin Alpha-1) |
| Synonyms | TA1; Thymalfasin |
| PubChem CID | 16130571 |
| Molecular Formula | C129H215N33O55 |
| Molecular Weight | ≈ 3108.3 g/mol |
| Physical Appearance | White to off-white lyophilized powder |
| Sequence Length | 28 amino acids; N-acetylated |
| Container | 3 mL glass vial (5mg net content) |
| Purity | ≥99% verified by HPLC & MS (lot COA via on-vial QR) |
| Solubility | Soluble in sterile water or compatible buffers; gentle inversion/swirl recommended. If required by your SOP, 0.22 µm filter-sterilize after reconstitution. |
| Intended Use | Laboratory research only (RUO). Not for human or animal use. |
Molecular Structure
Key Features of Peptide Tech
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Potential Applications in Research
Strictly in-vitro, cell-based, or biochemical experiments. No health, diagnostic, or therapeutic claims.
- Innate-immune reporter assays (e.g., NF-κB/IRF activation) in engineered cell lines to quantify pathway engagement under controlled stimuli.
- Dendritic-cell phenotype studies profiling maturation markers (e.g., CD80/CD86, MHC expression) and cytokine panels via ELISA/multiplex.
- T-cell co-culture models assessing antigen-presentation readouts and downstream signaling in vitro.
- Peptide stability & recovery workflows (LC–MS/MS, RP-HPLC) across buffers, temperatures, and freeze–thaw cycles.
- Uptake/localization assays with labeled peptide in live-cell imaging to examine internalization and trafficking kinetics.
Quality, Storage & Handling
Each lot is confirmed by HPLC (purity) and MS (identity); QR on the vial links to full batch data. Independent U.S. labs verify purity, quantity, and endotoxin.
- Storage (lyophilized): −20 °C long term or 2–8 °C short term; keep desiccated and light-protected.
- After reconstitution: Aliquot and store at ≤−20 °C (or −80 °C per SOP); avoid repeated freeze–thaw cycles.
- Reconstitution tips: Use sterile water or appropriate buffer; gently swirl to dissolve; filter-sterilize only if required by your assay.
Shipping & Fulfillment
Ships with validated cold-chain packaging. In-stock orders placed before the daily cutoff ship the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included; international shipping available where permitted.
Compliance & RUO Disclaimer
For laboratory research only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, ingestion, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines.
FAQs
- Is this intended for human or veterinary use?
- No. This product is sold strictly as RUO and must not be used in humans or animals.
- What purity do you provide?
- Each 5 mg vial is ≥99% by HPLC with MS identity confirmation; third-party testing is performed on every lot (see COA via QR).
- How should I reconstitute it?
- Use sterile water or a compatible buffer; gently invert until fully dissolved. If your protocol requires sterility, pass through a 0.22 µm filter and aliquot to avoid repeat freeze–thaw.
- What in-vitro assays is Thymosin Alpha-1 commonly used in?
- Typical RUO applications include innate-immune pathway reporters, dendritic-cell maturation panels, T-cell co-culture models, and LC–MS/MS method development.
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