Semax 5 mg — a heptapeptide analog of the ACTH(4–10) motif — from Peptide Tech is a premium, lyophilized research-use-only (RUO) reagent supplied at ≥99% purity (HPLC & MS verified). The sequence Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP) is packaged for rigorous in-vitro neurobiology, cell-signaling, and analytical method-development work where sequence fidelity, batch traceability, and cold-chain integrity matter.
Specifications
| Property | Details |
|---|---|
| Product Type | Synthetic heptapeptide (ACTH(4–10) analog) |
| Synonyms | Semax; ACTH(4–10) analog peptide |
| Sequence (1-letter) | MEHFPGP |
| Sequence (3-letter) | Met-Glu-His-Phe-Pro-Gly-Pro |
| Salt / Counter-ion | Typically acetate; see lot-matched COA for confirmation |
| CAS / Registry | May vary by salt form; see COA for identifiers |
| Molecular Formula / MW | Sequence-dependent; reported on COA |
| Physical Appearance | White to off-white lyophilized powder |
| Container | 3 mL glass vial (5 mg net content) |
| Purity | ≥99% verified by HPLC & MS (batch COA via on-vial QR) |
| Solubility | Readily soluble in sterile water or neutral aqueous buffers; prepare fresh. If required by SOP, 0.22 µm filter after reconstitution. |
| Intended Use | Laboratory research only (RUO). Not for human or animal use. |
Molecular Structure
Linear heptapeptide with the sequence MEHFPGP. For lot-specific identifiers (salt form, exact formula/MW) and a structural rendering, scan the on-vial QR to access the COA.
Key Features of Peptide Tech
- Same-Day Shipping (Mon–Fri, on in-stock items)
- GMP-Aligned Lyophilized Peptides
- USA Made
- 24/7 Support
- Price Match Guarantee
- Batch Tracking with QR Code Verification
- 3rd-Party U.S. Lab Testing — purity, quantity, endotoxin
- Cold-Chain Shipping — Always (no paid upgrade)
- Worldwide Shipping
- All Major Payments Accepted
- Text & Email Order Updates
- 2-Day FedEx/UPS Shipping Standard
- Cheapest Overnight Rates
- Largest Variety of Peptides & Bioregulators
Potential Applications in Research
Strictly in-vitro, cell-based, or biochemical experiments. No health, diagnostic, or therapeutic claims.
- Neuropeptide pathway profiling in neuronal or neuroendocrine cell models using reporter assays (e.g., CRE/ERK) under defined stimulation paradigms.
- Transcriptomic panels (qPCR/RNA-seq) to quantify peptide-dependent gene responses during nutrient or cytokine stress in culture.
- Peptidase stability & uptake studies in serum or conditioned media with RP-HPLC/LC–MS quantitation.
- Synaptic marker readouts (e.g., PSD-related proteins) via immunoblot or high-content imaging in standardized media conditions.
- Analytical method development (HPLC/LC–MS/MS) for identity, purity, recovery, and matrix effects across buffers and temperatures.
Quality, Storage & Handling
Every lot is confirmed by HPLC (purity) and MS (identity); batch COA is accessible via the on-vial QR. Independent U.S. labs verify purity, quantity, and endotoxin.
- Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
- After reconstitution: Aliquot and store at ≤−20 °C (or −80 °C per SOP); avoid repeated freeze–thaw cycles.
- Reconstitution tips: Use sterile water or suitable buffer; gently swirl/invert to dissolve; 0.22 µm filter only if required by your assay.
Shipping & Fulfillment
Ships with validated cold-chain packaging. In-stock orders placed before the daily cutoff ship the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included; international shipping available where permitted.
Compliance & RUO Disclaimer
For laboratory research only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, ingestion, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines.
FAQs
- Is this for human or veterinary use?
- No. This product is sold strictly as RUO and must not be used in humans or animals.
- What purity do you provide?
- Each 5 mg vial is ≥99% by HPLC with MS identity confirmation; third-party testing is performed on every lot (see COA via QR).
- What’s the exact salt form?
- Most lots are provided as the acetate salt. Refer to the lot-matched COA/label for confirmed counter-ion and identifiers.
- How should I reconstitute it?
- Use sterile water or a compatible buffer; gently invert until dissolved. If your protocol requires sterility, pass through a 0.22 µm filter and aliquot to avoid repeat freeze–thaw.
- Which in-vitro assays is Semax commonly used in?
- Typical RUO applications include neuropeptide pathway reporters, stress-response transcriptomics, peptidase-stability/uptake studies, and HPLC/LC–MS method development.
Explore More
Browse additional research peptides and accessories at Peptide Tech.














