Overview
Specifications
| Property | Details |
|---|---|
| Product Type | PEGylated peptide (MGF / IGF-1Ec E-peptide conjugate) |
| CAS / Registry | Not assigned for this conjugate (PEGylated mixtures typically lack single-compound CAS) |
| PubChem | Not applicable (heterogeneous PEG conjugate; see COA for identifiers) |
| Molecular Formula / MW | Lot-specific due to PEG chain length/dispersion; reported on the COA |
| Base Peptide | Mechano Growth Factor (IGF-1Ec) E-peptide, 24 aa (sequence and PEGylation site reported on COA) |
| PEG Details | Medical-grade PEG; nominal average MW and linkage chemistry are lot-specified on COA |
| Physical Appearance | White to off-white lyophilized powder |
| Container | 3 mL glass vial (2 mg net content) |
| Purity | ≥99% (peptide content) verified by HPLC & MS; third-party U.S. lab tested |
| Solubility | Readily soluble in sterile water or neutral aqueous buffers; mix gently to minimize foaming. If required by SOP, 0.22 µm filter after reconstitution. |
| Intended Use | Laboratory research only (RUO). Not for human or animal use. |
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Potential Applications in Research
Strictly in-vitro, cell-based, or biochemical experiments. No health, diagnostic, or therapeutic claims.
- IGF-axis pathway mapping (e.g., Akt/ERK readouts) in muscle-derived or engineered cell lines under controlled serum/nutrient conditions.
- Myoblast proliferation & migration assays (scratch/transwell) to quantify dose-dependent effects on motility and morphology in vitro.
- Extracellular-matrix (ECM) marker panels (collagen, MMP/TIMP) by ELISA/immunoblot to characterize matrix-remodeling signatures.
- Receptor/ligand screening in heterologous systems to compare analogs and map concentration–response relationships.
- Analytical method development for PEG-conjugates (RP-HPLC, SEC, LC–MS) covering identity, PEG distribution, recovery, and stability.
Quality, Storage & Handling
Each lot is confirmed by HPLC (purity) and MS (identity); QR on the vial links to the batch COA. Independent U.S. labs verify purity, quantity, and endotoxin.
- Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
- After reconstitution: Aliquot and store at ≤−20 °C (or −80 °C per SOP); avoid repeated freeze–thaw cycles.
- Reconstitution tips: Use sterile water or compatible buffer; gently swirl/invert (PEG can foam). If required, 0.22 µm filter-sterilize.
- Assay notes: Confirm buffer ionic strength and pH; document PEG content if your analytics require mass-normalized dosing.
Shipping & Fulfillment
Ships with validated cold-chain packaging. In-stock orders placed before the daily cutoff ship the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included; international shipping available where permitted.
Compliance & RUO Disclaimer
For laboratory research only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, ingestion, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines. COAs available via QR or upon request.
FAQs
- Is this the PEGylated form of MGF?
- Yes. This product is a PEG-conjugated MGF (IGF-1Ec E-peptide). The nominal PEG size/linkage chemistry is listed on the lot COA.
- Does PEG affect the exact molecular weight?
- Yes — PEG conjugates are inherently heterogeneous. The COA reports the nominal PEG average and the calculated mass range for the lot.
- What purity do you provide?
- Each 2 mg vial is ≥99% (HPLC) with MS identity confirmation; third-party testing is performed on every lot (see COA via QR).
- How should I reconstitute it?
- Use sterile water or a compatible buffer; mix gently to avoid foaming. If your SOP requires sterility, pass through a 0.22 µm filter and aliquot to avoid repeat freeze–thaw.
- Which in-vitro assays is PEG-MGF commonly used in?
- Typical RUO uses include IGF-axis signaling panels, myoblast migration/proliferation assays, ECM marker profiling, and LC–MS/SEC analytics for PEGylated peptides.
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