$23.95
Gonadorelin (GnRH) 2 mg from Peptide Tech is a premium, lyophilized research-use-only (RUO) decapeptide supplied at ≥99% purity (HPLC & MS verified). This peptide—also known as luteinizing hormone–releasing hormone (LHRH)—is widely used in in-vitro receptor-binding, calcium-mobilization, and pathway-mapping studies where sequence fidelity and batch traceability are essential.
Specifications
| Property | Details |
|---|---|
| CAS Number | 33515-09-2 (free base) |
| Chemical Name | PyroGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 (Gonadorelin; GnRH; LHRH) |
| PubChem CID | 638793 |
| Molecular Formula | C55H75N17O13 |
| Molecular Weight | ≈ 1182.31 g/mol |
| Physical Appearance | White to off-white lyophilized powder |
| Sequence | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 |
| Container | 3 mL glass vial (2 mg net content) |
| Purity | ≥99% verified by HPLC & MS (lot COA via on-vial QR) |
| Solubility | Soluble in sterile water or compatible aqueous buffer; optimize pH/ionic strength for your assay and filter-sterilize if required |
| Intended Use | Laboratory research only (RUO). Not for human or animal use. |
Molecular Structure
Key Features of Peptide Tech
- Same-Day Shipping (Mon–Fri, on in-stock items)
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Potential Applications in Research
Strictly in-vitro, cell-based, or biochemical experiments. No health claims or clinical/veterinary use.
- GnRH receptor (GNRHR) calcium-mobilization assays in receptor-positive cells (e.g., CHO/HEK293 lines) to map Gq/PLC–IP3–Ca2+ signaling and oscillation patterns.
- Radioligand/competition binding with iodinated GnRH analogs to determine affinity/kinetics and rank-order potency across ligands.
- Pathway mapping (PLC/IP3, PKC, and ERK/MAPK) via reporter assays, Western blotting, and high-content imaging in standardized media conditions.
- Receptor internalization & β-arrestin recruitment using confocal/BRET/ELISA readouts to study desensitization and trafficking phenotypes.
- Analytical method development (RP-HPLC and LC–MS/MS) for peptide detection/quantitation, matrix effects, and stability profiling.
Quality, Storage & Handling
Every lot is confirmed by HPLC (purity) and MS (identity); batch COA is accessible via on-vial QR. Independent U.S. labs verify purity, quantity, and endotoxin.
- Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
- After reconstitution: Aliquot and store at ≤−20 °C (or −80 °C per SOP); avoid repeated freeze–thaw.
- Reconstitution tips: Use sterile water or suitable buffer; gentle inversion/brief sonication can aid dissolution; filter-sterilize if required.
Shipping & Fulfillment
Ships with validated cold-chain packaging. In-stock orders placed before the daily cutoff ship the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included; international shipping available where permitted.
Compliance & RUO Disclaimer
For laboratory research only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, clinical, veterinary, or diagnostic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines. COAs available upon request or via QR.
FAQs
- Is this for human or veterinary use?
- No. This product is sold strictly as RUO and must not be used in humans or animals.
- What purity do you provide?
- Each 2 mg vial is ≥99% by HPLC with MS identity confirmation; third-party testing is performed on every lot (see COA via QR).
- How should I reconstitute it?
- Use sterile water or a compatible buffer; gently invert until dissolved. If your protocol requires, 0.22 µm filter-sterilize and aliquot to avoid repeat freeze–thaw.
- What in-vitro assays is Gonadorelin commonly used in?
- Typical RUO uses include GNRHR Ca2+ signaling, radioligand binding, ERK/MAPK pathway studies, β-arrestin/internalization workflows, and LC–MS/MS method development.
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