Name: MT1 10mg - Template
Price: 24.95 USD
Availability: InStock

MT‑1 10 mg (Melanotan I; Afamelanotide; NDP‑α‑MSH) from Peptide Tech is a premium, lyophilized research‑use‑only (RUO) peptide supplied at ≥99% purity (HPLC & MS verified). This α‑MSH analog—Ac‑Ser‑Tyr‑Ser‑Nle‑Glu‑His‑D‑Phe‑Arg‑Trp‑Gly‑Lys‑Pro‑Val‑NH₂—is packaged for reproducible in‑vitro receptor pharmacology, melanocortin signaling, and analytical method‑development workflows requiring sequence fidelity, batch traceability, and cold‑chain integrity.

Specifications

Property	Details
Product	MT‑1 (Melanotan I / Afamelanotide) — lyophilized peptide, 10 mg
Chemical Name	Ac‑Ser‑Tyr‑Ser‑Nle‑Glu‑His‑D‑Phe‑Arg‑Trp‑Gly‑Lys‑Pro‑Val‑NH₂
Synonyms	Melanotan I; Afamelanotide; NDP‑α‑MSH; MT‑1
Sequence	Ac‑SY S Nle E H D‑F R W G K P V‑NH₂ (single‑letter: Ac‑S Y S X E H dF R W G K P V‑NH₂; X = norleucine)
CAS Number	75921‑69‑6 (sequence reference)
PubChem CID	16130945 (Afamelanotide)
Molecular Formula	C₇₈H₁₁₁N₂₁O₁₉
Molecular Weight	≈ 1646.88 g/mol
Appearance	White to off‑white lyophilized powder
Container	3 mL Type I glass vial; butyl stopper; flip‑off seal
Purity / Identity	≥99% by HPLC; identity by MS (batch COA via on‑vial QR)
Counter‑ion	Typically acetate (confirm on COA)
Solubility	Soluble in sterile water or neutral aqueous buffers; if needed, pre‑wet with ≤0.1% acetic acid and bring to buffer. Filter (0.22 µm) if sterility is required by your SOP.
Storage (lyophilized)	−20 °C long‑term (desiccated, light‑protected)
After Reconstitution	Aliquot; store at ≤ −20 °C (or −80 °C per SOP); avoid repeat freeze–thaw cycles.
Intended Use	RUO only. Not for human or animal use.

Molecular Structure

MT‑1 / Afamelanotide 2D structure — PubChem CID 16130945 — View on PubChem (CID 16130945)

Key Features of Peptide Tech

Same‑Day Shipping (Mon–Fri, on in‑stock items)
GMP‑Aligned lyophilization & documentation
USA‑Made peptides
24/7 Support & Price Match Guarantee
Batch QR for instant COA & chain‑of‑custody verification
3rd‑Party U.S. Lab Testing — purity, quantity, endotoxin
Cold‑Chain Shipping — Always (no paid upgrade)
Worldwide Shipping; all major payments accepted
Text & Email order updates; 2‑Day FedEx/UPS standard with low‑cost overnight
Largest Variety of peptides & bioregulators

Potential Applications in Research (RUO)

Strictly for laboratory research. No health, diagnostic, or therapeutic claims.

Melanocortin receptor pharmacology — quantify potency/efficacy at human MC1R/MC3R/MC4R using cAMP reporters or β‑arrestin recruitment in transiently or stably expressing cell lines.
Ligand bias & signaling kinetics — compare MT‑1 vs. α‑MSH and other analogs across second‑messenger profiles (cAMP/IP, ERK phosphorylation) under serum‑defined conditions.
Binding/competition assays — membranes or intact cells to determine K_i, association/dissociation rates, and rank‑order potency among melanocortin ligands.
Photobiology/cellular pigmentation models — assess MITF/tyrosinase axis readouts and melanosome dynamics in melanocyte cultures (in‑vitro only) with standardized light/UV exposure paradigms.
Analytical method development — RP‑HPLC/LC–MS(/MS) for identity, purity, recovery, and forced‑degradation stability across buffers and temperatures.

Citations (selected)

Schiöth, Helgi B., et al. Melanocortin receptors: pharmacology and signaling (overview of MC system).
Afamelanotide (NDP‑α‑MSH) primary registry/monograph entries for sequence, formula, and identifiers.
Standard cAMP and β‑arrestin assay methods in GPCR pharmacology literature.

Quality, Storage & Handling

Each lot is confirmed by HPLC (purity) and MS (identity); the on‑vial QR links to the batch COA. Independent U.S. labs verify purity, quantity, and endotoxin.

Storage (lyophilized): −20 °C long‑term or 2–8 °C short‑term; keep desiccated and protected from light.
After reconstitution: Aliquot and store at ≤ −20 °C (or −80 °C per SOP); avoid repeated freeze–thaw cycles.
Reconstitution tips: Use sterile water or suitable buffer; gently swirl/invert to dissolve. If sterility is required, 0.22 µm filter and aliquot promptly.

Shipping & Fulfillment

Ships with validated cold‑chain packaging. In‑stock orders placed before the daily cutoff ship the same day. 2‑Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included; international shipping available where permitted.

Compliance & RUO Disclaimer

For laboratory research only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, ingestion, diagnostic, or therapeutic applications. Purchasers warrant appropriate qualifications and compliance with applicable regulations and institutional policies.

FAQs

Is MT‑1 the same as MT‑II?: No. MT‑1 (Afamelanotide) is the 13‑mer NDP‑α‑MSH analog listed above. MT‑II (Bremelanotide/PT‑141) is a distinct cyclic heptapeptide.
Do you provide a PubChem image?: Yes—the 2D structure above is rendered from PubChem CID 16130945 for Afamelanotide (NDP‑α‑MSH).
What purity do you provide?: Each 10 mg vial is ≥99% by HPLC with MS identity confirmation; third‑party testing is performed on every lot (COA via on‑vial QR).
How should I reconstitute it?: Dissolve in sterile water or a compatible buffer; gently invert until fully dissolved. If your SOP requires sterility, 0.22 µm filter and aliquot to avoid repeat freeze–thaw.