Name: MOTS-c 10mg - Template
Price: 34.95 USD
Availability: InStock

MOTS-c 10 mg (Mitochondrial Open Reading Frame of the 12S rRNA—type c) from Peptide Tech is a premium, lyophilized research-use-only (RUO) peptide supplied at ≥99% purity (HPLC & MS verified). This 16–amino acid mitochondrial-derived peptide (MRWQEMGYIFYPRKLR) is widely used in in-vitro cell signaling, stress-response, and bioenergetics workflows where sequence fidelity, analytical confirmation, and cold-chain integrity matter.

Specifications

Property	Details
CAS Number	1627580-64-6
Chemical Name	Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (MOTS-c)
PubChem CID	146675088
Molecular Formula	C₁₀₁H₁₅₂N₂₈O₂₂S₂
Molecular Weight	≈ 2174.6 g/mol
Physical Appearance	White to off-white lyophilized powder
Sequence	MRWQEMGYIFYPRKLR (16 aa)
Container	3 mL glass vial (10 mg net content)
Purity	≥99% verified by HPLC & MS (lot COA via on-vial QR)
Solubility	Soluble in sterile water or compatible aqueous buffer; gentle agitation recommended. If required by protocol, 0.22 µm filter-sterilize.
Intended Use	Laboratory research only (RUO). Not for human or animal use.

Molecular Structure

Key Features of Peptide Tech

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Potential Applications in Research

Strictly in-vitro, cellular, or biochemical contexts. No health, diagnostic, or therapeutic claims.

AMPK pathway activation assays in skeletal-muscle or HEK/CHO models (western blot/immuno-ELISA, reporter systems) under defined nutrient-stress conditions.
Cellular stress-response workflows (oxidative or metabolic stress) profiling transcriptional programs and stress-adaptation markers following peptide exposure.
Mitochondrial bioenergetics readouts (OCR/ECAR) using extracellular flux analysis to map alterations in substrate utilization and coupling efficiency.
Nuclear translocation studies of peptide-stimulated factors during metabolic stress (live-cell imaging/high-content microscopy, time-lapse kinetics).
Kinase-interaction and modulation screens (e.g., CK2 activity assays) to explore peptide-dependent signaling changes in vitro.
Analytical method development (LC–MS/MS) for identity, stability, and recovery in relevant assay matrices (buffer/media).

Quality, Storage & Handling

Each lot is confirmed by HPLC (purity) and MS (identity); QR on the vial links to the batch COA. Independent U.S. labs verify purity, quantity, and endotoxin.

Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
After reconstitution: Aliquot and store at ≤−20 °C (or −80 °C per SOP); avoid repeated freeze–thaw cycles.
Reconstitution tips: Use sterile water or suitable buffer; gently invert to dissolve (brief sonication if needed); filter-sterilize only if required by your assay.

Shipping & Fulfillment

Ships in validated cold-chain packaging. In-stock orders placed before the daily cutoff ship the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included; international shipping available where permitted.

Compliance & RUO Disclaimer

For laboratory research only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, ingestion, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines. COAs available upon request or via QR.

FAQs

Is this intended for human or veterinary use?: No. This product is sold strictly as RUO and must not be used in humans or animals.
What purity do you provide?: Each 10 mg vial is ≥99% by HPLC with MS identity confirmation; third-party testing is performed on every lot (see COA via QR).
How should I reconstitute it?: Use sterile water or a compatible aqueous buffer; gently invert until fully dissolved. If your protocol requires sterility, pass through a 0.22 µm filter and aliquot.
Which in-vitro assays is MOTS-c commonly used in?: Typical RUO applications include AMPK signaling, stress-response profiling, mitochondrial bioenergetics (OCR/ECAR), kinase-interaction assays, and LC–MS/MS method validation.