CJC-1295 (no DAC) — 5 mg Lyophilized Powder (RUO)

CJC-1295 (no DAC)—also known in research settings as a modified GHRH(1–29) analogue—is supplied by Peptide Tech as a 5 mg lyophilized powder in a sterile research vial. Manufactured under GMP-aligned procedures with batch-level traceability, this material is intended strictly for laboratory research use only and is suitable for in-vitro, cell-based, and analytical workflows exploring GHRH-receptor pharmacology, pathway mapping, and stability/method development—without any clinical or human-use claims.

Specifications

Property	Details
Product Name	CJC-1295 (no DAC) — 5 mg
Form	Lyophilized powder (freeze-dried)
Container	Sterile Type I glass vial (research-grade closure), 3 mL nominal
Appearance	White to off-white lyophilized cake/powder
Chemical Identity	Modified GHRH(1–29) peptide analogue (no Drug Affinity Complex)
CAS Number	Not available / construct-specific
PubChem CID	Not available for this construct
Molecular Formula / Weight	Construct-dependent; see lot COA (do not assume equivalence to DAC forms)
Sequence	Modified GHRH(1–29); specific substitutions listed on the lot COA
Purity / ID	Research-grade; identity and purity confirmed per lot (e.g., MS/HPLC)—see COA
Solubility (general)	Reconstitute with sterile water or compatible buffer; adjust pH/ionic strength per assay. If required by your protocol, filter through 0.22 µm.
Storage	Store sealed, desiccated, and protected from light. Short-term: 2–8 °C. Long-term: ≤−20 °C. After reconstitution, aliquot and avoid repeated freeze–thaw.
Intended Use	For laboratory research use only (RUO); not for human or animal use, ingestion, diagnostic, therapeutic, or veterinary applications.

Key Features — Peptide Tech

• Same-Day Shipping (Mon–Fri, on in-stock items)
• GMP-Aligned peptide synthesis, lyophilization & packaging
• USA Made with QR batch tracking & COA access
• Third-Party U.S. Lab Testing — purity, quantity; endotoxin where applicable
• Cold-Chain Shipping — Always (no paid upgrade)
• Worldwide Shipping with compliant documentation
• Text & Email Order Updates; 2-Day FedEx/UPS Standard & economical Overnight options

Potential Applications in Research

Strictly non-clinical; focus on in-vitro, cell-based, and analytical studies. No health or therapeutic claims.

• GHRH-R signaling assays — quantify Gs–cAMP/PKA activation (e.g., CRE-luciferase, cAMP HTRF) and downstream ERK/MAPK readouts in GHRH-receptor–expressing cells.
• Radioligand/competition binding — determine affinity/selectivity at GHRH-R and generate K_i/pIC₅₀ values under controlled assay conditions.
• Receptor internalization & β-arrestin recruitment — compare trafficking kinetics vs. native GHRH and other analogues using live-cell biosensors.
• Stability / forced-degradation studies — pH, oxidative, thermal, and light stress mapping with stability-indicating HPLC/LC-MS methods.
• Formulation & recovery screening — buffer selection, adsorption to plastics/filters, and reconstitution/recovery benchmarking for assay reproducibility.

Quality, Storage & Handling

• Quality: Each lot is confirmed by MS/HPLC (see COA). Third-party testing performed where applicable.
• Reconstitution: Bring vial to room temperature to prevent condensation; add sterile solvent; swirl gently to dissolve; aliquot promptly.
• Post-Reconstitution: Store aliquots at ≤−20 °C and minimize freeze–thaw cycles.

Shipping & Fulfillment

Ships with validated cold-chain packaging. In-stock orders placed before the daily cutoff dispatch the same day. 2-Day FedEx/UPS is standard, with overnight options. Automated text/email updates included; international service available where permitted.

Compliance & RUO Disclaimer

For laboratory research use only. Not a drug, food, or cosmetic. Not for human or animal use, ingestion, diagnostic, therapeutic, or veterinary applications. Purchasers must be qualified to handle RUO materials and comply with applicable laws and institutional policies.

FAQs

How is “no DAC” different from CJC-1295 with DAC?

“No DAC” indicates a modified GHRH(1–29) analogue without the Drug Affinity Complex moiety. Do not assume equivalence in sequence, mass, or kinetics; refer to the lot COA.

Is a full sequence provided?

The specific substitution pattern is listed on the lot-specific COA. If you require a particular construct, contact support before ordering.

Recommended starting solvent?

Begin with sterile water or a neutral buffer; adjust pH/ionic strength for your assay. If sterility is required, pass through a 0.22 µm filter after complete dissolution.

How do I access the COA?

Scan the vial’s QR code or contact support to receive batch documentation, including identity, purity, and analytical method notes.