GHRP-6 10 mg from Peptide Tech is a premium, lyophilized research-use-only (RUO) hexapeptide supplied at ≥99% purity (HPLC & MS verified). As a selective GHSR-1a (ghrelin receptor) agonist, it’s ideal for in-vitro GPCR signaling, ligand-binding, and analytical method-development workflows where sequence fidelity, documentation, and cold-chain integrity are essential.

Specifications

Property	Details
Chemical Name	Growth Hormone-Releasing Peptide-6 (GHRP-6)
Synonyms	GHRP-6; Growth hormone secretagogue hexapeptide
CAS Number	87616-84-0
PubChem CID	5486806
Sequence	H-His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂
Molecular Formula	C₄₆H₅₆N₁₂O₆
Molecular Weight	≈ 873.03 g/mol
Counter-ion	Typically acetate; see lot-matched COA
Appearance	White to off-white lyophilized powder
Content per Vial	10 mg
Container	3 mL Type I glass vial
Purity / ID	≥99% by HPLC; identity by MS (batch COA via on-vial QR)
Solubility	Soluble in sterile water or neutral aqueous buffers; a minimal 0.1% acetic acid pre-wet can aid dissolution. If required by your SOP, 0.22 µm filter after reconstitution.
Intended Use	Laboratory research only (RUO). Not for human or animal use.

Molecular Structure

Key Features of Peptide Tech

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3rd-Party U.S. Lab Testing — purity, quantity, endotoxin
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Potential Applications in Research

Strictly for in-vitro, cell-based, or biochemical experiments. No health, diagnostic, or therapeutic claims.

GHSR-1a signaling — calcium flux (e.g., Fluo-4) or IP-One assays to quantify potency/efficacy and receptor desensitization under serum-defined conditions.
β-arrestin recruitment & internalization — BRET/ELISA/confocal workflows to profile trafficking and potential biased signaling at GHSR-1a.
Radioligand/competition binding — membranes or intact cells to determine K_i, on/off-rates, and rank-order potency versus related GHS agonists.
Pathway mapping — PLC/IP₃/Ca²⁺ cross-talk to ERK/Akt using reporter panels and immunoblotting in defined media.
Analytical method development — RP-HPLC/LC–MS/MS for identity, stability, and recovery across buffers and temperatures.

Quality, Storage & Handling

Each lot is confirmed by HPLC (purity) and MS (identity); the on-vial QR links to the batch COA. Independent U.S. labs verify purity, quantity, and endotoxin.

Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
After reconstitution: Aliquot and store at ≤ −20 °C (or −80 °C per SOP); avoid repeated freeze–thaw cycles.
Reconstitution tips: Use sterile water or compatible buffer; gently swirl/invert to dissolve. If sterility is required, 0.22 µm filter and aliquot promptly.

Shipping & Fulfillment

Ships with validated cold-chain packaging. In-stock orders placed before the daily cutoff ship the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included; international shipping available where permitted.

Compliance & RUO Disclaimer

For laboratory research only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, ingestion, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines.

FAQs

Is GHRP-6 the same as GHRP-2?: No. GHRP-2 (Pralmorelin) is a different hexapeptide. GHRP-6 has the sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂; verify performance in your specific assay format.
What purity do you provide?: Each 10 mg vial is ≥99% by HPLC with MS identity confirmation; third-party testing is performed on every lot (COA via on-vial QR).
How should I reconstitute it?: Dissolve in sterile water or a compatible buffer; gently invert until fully dissolved. If your protocol requires sterility, pass through a 0.22 µm filter and aliquot to avoid repeat freeze–thaw.
Which in-vitro assays is GHRP-6 commonly used in?: Typical RUO uses include GHSR Ca²⁺/IP-One assays, β-arrestin/internalization workflows, binding/competition experiments, and HPLC/LC–MS method development.