Vesugen 20mg

Overview

Vesugen 20 mg (Lys–Glu–Asp, “KED”) from Peptide Tech is a premium, lyophilized research-use-only (RUO) tripeptide supplied at ≥99% purity (HPLC & MS verified). This sequence-defined peptide is packaged for reproducible in-vitro endothelial, peptide-transport, and analytical method-development studies where documentation, batch traceability, and cold-chain integrity are essential.

Specifications

Property	Details
Product	Vesugen (KED) — 20 mg lyophilized peptide
Chemical Name	H-Lys-Glu-Asp-OH (L-lysyl-L-glutamyl-L-aspartic acid)
Synonyms	KED; Lys-Glu-Asp; Vesugen; lysylglutamyl aspartic acid
CAS Number	204271-66-9 (sequence: Lys-Glu-Asp)
PubChem CID	87571363
Sequence	Lys–Glu–Asp (K-E-D)
Molecular Formula	C15H26N4O8
Molecular Weight	≈ 390.39 g/mol
Appearance	White to off-white lyophilized powder
Content per Vial	20 mg
Container	3 mL Type I glass vial; butyl stopper; flip-off seal
Purity / Identity	≥99% by HPLC; identity by MS (batch COA via on-vial QR)
Solubility	Soluble in sterile water or neutral aqueous buffers. If your SOP requires, 0.22 µm filter after reconstitution.
Storage (lyophilized)	−20 °C long-term (desiccated, light-protected)
After Reconstitution	Aliquot; store at ≤ −20 °C (or −80 °C per SOP); avoid repeat freeze–thaw
Intended Use	Research Use Only (RUO). Not for human or animal use.

Molecular Structure

Key Features of Peptide Tech

• Same-Day Shipping (Mon–Fri, on in-stock items)
• GMP-Aligned lyophilization & documentation
• USA-Made peptides
• 24/7 Support & Price Match Guarantee
• Batch QR for instant COA & chain-of-custody verification
• 3rd-Party U.S. Lab Testing — purity, quantity, endotoxin
• Cold-Chain Shipping — Always (no paid upgrade)
• Worldwide Shipping; all major payments accepted
• Text & Email order updates; 2-Day FedEx/UPS standard with low-cost overnight
• Largest Variety of peptides & bioregulators

Potential Applications in Research (RUO)

Strictly for laboratory research. No health, diagnostic, or therapeutic claims.

• Endothelial network formation (2D) — quantify tube-formation metrics (nodes, meshes, total length) in HUVEC/HMEC-1 assays on basement-membrane matrix under defined KED exposures; include vehicle and positive controls.
• Microvessel sprouting (3D) — use human blood-vessel-on-a-chip systems to evaluate VEGF-dependent sprout initiation/elongation and barrier readouts with tripeptide treatment.
• Peptide-transporter profiling — assess PEPT1/PEPT2 uptake in Caco-2 or HEK over-expression systems to map short-peptide transport kinetics and sequence/charge determinants.
• Cell-state panels in neuroendocrine models — measure proliferation (Ki-67), apoptosis markers (e.g., p53 immunostaining/Western), and viability under controlled culture conditions.
• Analytical method development — establish RP-HPLC and LC–MS/MS for identity, purity, recovery, and forced-degradation stability across buffers and temperatures.

Citations (MLA)

1. Kvetnoy, I. M., et al. “Effect of Tripeptide Lys–Glu–Asp on Physiological Activity of Neuroimmunoendocrine System Cells.” Bulletin of Experimental Biology and Medicine, vol. 153, no. 4, 2012, pp. 563–566. https://doi.org/10.1007/s10517-012-1768-7
2. Pauty, Joris, et al. “A VEGF-Dependent Sprouting Angiogenesis Assay Based on a Human Blood-Vessel-on-a-Chip.” EBioMedicine, vol. 27, 2018, pp. 225–236. Link
3. DeCicco-Skinner, Kathleen L., et al. “Assays to Examine Endothelial Cell Migration, Tube Formation, and Gene Expression.” Methods in Molecular Biology, 2014, pp. 255–264. Link
4. Brandsch, Matthias. “Drug Transport via the Intestinal Peptide Transporter PepT1.” Drug Discovery Today: Technologies, vol. 9, no. 2, 2012/2013, pp. e7–e14. Link

Quality, Storage & Handling

Every lot is confirmed by HPLC (purity) and MS (identity); the on-vial QR links to the batch COA. Independent U.S. labs verify purity, quantity, and endotoxin.

• Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
• After reconstitution: Aliquot and store at ≤ −20 °C (or −80 °C per SOP); avoid repeated freeze–thaw cycles.
• Reconstitution tips: Use sterile water or suitable buffer; gently swirl/invert to dissolve. If sterility is required, pass through a 0.22 µm filter and aliquot promptly.

Shipping & Fulfillment

Ships with validated cold-chain packaging. In-stock orders placed before the daily cutoff ship the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included; international shipping available where permitted.

Compliance & RUO Disclaimer

For laboratory research only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, ingestion, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines.

FAQs

Is Vesugen the same as Vilon or Thymogen?

No. Vesugen is the tripeptide Lys–Glu–Asp (KED). Vilon is the dipeptide Lys–Glu (KE), and Thymogen is Glu–Trp (EW). Always verify the exact sequence required by your protocol.

What purity do you provide?

Each 20 mg vial is ≥99% by HPLC with MS identity confirmation; third-party testing is performed on every lot (COA via on-vial QR).

How should I reconstitute it?

Dissolve in sterile water or a compatible buffer; gently invert until fully dissolved. If your SOP requires sterility, 0.22 µm filter and aliquot to avoid repeat freeze–thaw.

Which in-vitro assays are common?

Typical RUO uses include tube-formation/sprouting assays, PEPT1/PEPT2 transport studies, cell-state panels (Ki-67/p53), and HPLC/LC–MS method development (see citations above).

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Always read the label and use products as directed. Consult a qualified professional where appropriate.