Fasoracetam (Powder) — 1 g, Research Grade (RUO)

Fasoracetam (NS-105; NFC-1; LAM-105) is a small-molecule racetam supplied by Peptide Tech as a white crystalline powder for laboratory research use only. Each sealed jar contains 1 gram of research-grade material with batch-level traceability and COA access—ideal for in-vitro, cellular, and analytical workflows such as receptor-signaling assays, radioligand/competition binding, and stability-indicating method development.

Specifications

Molecular Structure

Key Features — Peptide Tech

• Same-Day Shipping (Mon–Fri, in-stock)
• GMP-Aligned synthesis & packaging
• USA Made with QR batch tracking
• COA Access — identity/purity per lot
• Third-Party U.S. Lab Testing (as applicable)
• Cold-Chain Shipping — Always (no paid upgrade)
• Worldwide Shipping with compliant documentation
• Text & Email Order Updates; 2-Day FedEx/UPS Standard & economical Overnight options

Potential Applications in Research

Strictly non-clinical; focus on in-vitro, cellular, and biochemical contexts. No human-use claims.

• mGluR signaling assays — evaluate metabotropic glutamate receptor (mGluR) pathway activation (e.g., cAMP, IP₃/Ca²⁺, ERK/MAPK) in receptor-expressing cell lines; explore variants impacting glutamatergic networks.
• Radioligand/competition binding — quantify affinity/selectivity at targeted GPCRs (e.g., mGluR subtypes) and derive K_d/K_i under controlled conditions.
• Chronic exposure paradigms — investigate receptor expression/adaptation phenomena (e.g., reports of GABA_B receptor changes in preclinical models) using defined in-vitro protocols.
• Neuronal culture phenotyping — measure calcium flux, membrane excitability, and transcriptional reporters tied to glutamatergic signaling.
• Analytical method development — stability-indicating HPLC/LC-MS/MS for small-molecule racetams; impurity profiling and forced-degradation studies.

Citations

• Elia, J., et al. “Fasoracetam in Adolescents with ADHD and Glutamatergic Gene Network Variants Disrupting mGluR Signaling.” Nature Communications, 2018. PubMed • PMC
• Niswender, C. M., & Conn, P. J. “Metabotropic Glutamate Receptors.” Pharmacological Reviews, 2010. PMC2904507
• Shimizu, T., et al. “Possible Involvement of GABA_B Receptor Up-Regulation after Repeated Administration of NS-105.” Jpn. J. Pharmacol., 1997. PubMed 9424016
• Sherman, S. M., & Guillery, R. W. “The Function of Metabotropic Glutamate Receptors in Thalamus and Cortex.” Front. Neural Circuits, 2013. PMC4747429

Quality, Storage & Handling

• Identity & Purity: See lot COA (e.g., HPLC, MS).
• Storage: Keep sealed, cool (2–8 °C preferred), dry, and protected from light; reseal promptly after opening.
• Handling: Use appropriate PPE; prepare solutions fresh; confirm solvent/pH compatibility and filter per SOP for sterile applications.

Shipping & Fulfillment

Ships with validated cold-chain packaging. In-stock orders placed before the daily cutoff dispatch the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included; international service available where permitted.

Compliance & RUO Disclaimer

For laboratory research use only. Not a drug, food, or cosmetic. Not for human or animal use, ingestion, diagnostic, therapeutic, or veterinary applications. Purchasers must be qualified to handle RUO materials and comply with applicable laws and institutional policies.