Pinealon 20 mg (EDR; Glu–Asp–Arg) from Peptide Tech is a premium, lyophilized research‑use‑only (RUO) tripeptide supplied at ≥99% purity (HPLC & MS verified). The sequence H‑Glu‑Asp‑Arg‑OH is prepared for rigorous in‑vitro neuronal/glial assays, epithelial models, and analytical method development—backed by lot traceability, independent third‑party testing, and validated cold‑chain logistics.
Specifications
| Property | Details |
|---|---|
| Product | Pinealon — lyophilized peptide, 20 mg |
| Chemical Name | H‑Glu‑Asp‑Arg‑OH (L‑glutamyl‑L‑aspartyl‑L‑arginine) |
| Synonyms | EDR; Glu‑Asp‑Arg; Pinealon |
| Sequence | Glu–Asp–Arg (E‑D‑R) |
| CAS Number | Not assigned (sequence‑defined RUO tripeptide) |
| PubChem CID | 23675314 (EDR, fragment-level entry) |
| Molecular Formula | C15H26N6O8 (free acid) |
| Molecular Weight | ≈ 418.40 g/mol (free acid; counter‑ion may alter apparent mass; verify on COA) |
| Appearance | White to off‑white lyophilized powder |
| Container | 3 mL Type I glass vial; butyl stopper; flip‑off seal |
| Purity / Identity | ≥99% by HPLC; identity by MS (batch COA via on‑vial QR) |
| Counter‑ion | Typically acetate (confirm on lot COA) |
| Solubility | Soluble in sterile water or neutral buffers; for rapid wetting at higher concentrations, pre‑wet with ≤0.1% acetic acid then bring to buffer. If sterility is required by your SOP, 0.22 µm filter after dissolution. |
| Storage (lyophilized) | −20 °C long‑term; store desiccated and protected from light. |
| After Reconstitution | Aliquot and store at ≤ −20 °C (or −80 °C per SOP); avoid repeat freeze–thaw cycles. |
| Intended Use | RUO only. Not for human or animal use. |
Molecular Structure
Key Features of Peptide Tech
- Same‑Day Shipping (Mon–Fri, on in‑stock items)
- GMP‑Aligned lyophilization & documentation
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- Batch QR for instant COA & chain‑of‑custody verification
- 3rd‑Party U.S. Lab Testing — purity, quantity, endotoxin
- Cold‑Chain Shipping — Always (no paid upgrade)
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- Text & Email order updates; 2‑Day FedEx/UPS standard with low‑cost overnight
- Largest Variety of peptides & bioregulators
Potential Applications in Research (RUO)
Strictly for laboratory research. No health, diagnostic, or therapeutic claims.
- Neuronal/glial cell assays — quantify gene/protein panels related to plasticity and stress responses after controlled EDR exposures; include viability/apoptosis controls and time‑course sampling.
- Epithelial barrier & migration — TEER and scratch‑wound assays in airway or intestinal lines to evaluate barrier dynamics and cytokine secretion under defined conditions.
- Oxidative‑stress workflows — ROS quantitation, antioxidant enzyme expression, and mitochondrial potential measurements in neural or epithelial models across media compositions.
- Peptide transport & stability — characterize uptake and metabolic stability of short acidic tripeptides in Caco‑2/HEK systems; quantify by LC–MS(/MS).
- Analytical method development — establish RP‑HPLC/LC–MS(/MS) identity, purity, recovery, and forced‑degradation stability across buffers, pH, and temperature.
Citations (selected)
- Khavinson, V. Kh., et al. Short peptide bioregulators — background on sequence‑defined tripeptides and neuronal/epithelial applications (review context).
- Brandsch, M. Peptide transporters PepT1/2 — methodology for di‑/tripeptide uptake studies.
- Standard in‑vitro TEER/scratch, ROS, and LC–MS quantitation protocols (Methods in Molecular Biology/JOVE style references).
Quality, Storage & Handling
Every lot is confirmed by HPLC (purity) and MS (identity); the on‑vial QR links to the batch COA. Independent U.S. labs verify purity, quantity, and endotoxin.
- Storage (lyophilized): −20 °C long‑term or 2–8 °C short‑term; keep desiccated and protected from light.
- After reconstitution: Aliquot promptly; store at ≤ −20 °C (or −80 °C per SOP). Avoid multiple freeze–thaw cycles.
- Reconstitution tips: Use sterile water or suitable buffer; gently swirl/invert to dissolve. If sterility is required, 0.22 µm filter and aliquot.
Shipping & Fulfillment
Ships with validated cold‑chain packaging. In‑stock orders placed before the daily cutoff ship the same day. 2‑Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included; international shipping available where permitted.
Compliance & RUO Disclaimer
For laboratory research only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, ingestion, diagnostic, or therapeutic applications. Purchasers warrant appropriate qualifications and compliance with applicable regulations and institutional policies.
FAQs
- Is Pinealon the same as Cartalax, Chonluten, or Vilon?
- No. Pinealon is the tripeptide Glu–Asp–Arg (EDR). Cartalax is Ala–Glu–Asp (AED), Chonluten is Glu–Asp–Pro (EDP), and Vilon is Lys–Glu (KE). Verify the sequence required by your assay.
- Do you provide a PubChem image?
- Yes—the 2D structure above is rendered from PubChem CID 23675314 for EDR (Glu–Asp–Arg).
- What purity do you provide?
- Each 20 mg vial is ≥99% by HPLC with MS identity confirmation; third‑party testing is performed on every lot (COA via on‑vial QR).
- How should I reconstitute it?
- Dissolve in sterile water or a compatible buffer; gently invert until fully dissolved. If your SOP requires sterility, 0.22 µm filter and aliquot to avoid repeat freeze–thaw.
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Always read the label and use products as directed. Consult a qualified professional where appropriate.









