GHRP-2 (Pralmorelin) 10 mg from Peptide Tech is a premium, lyophilized research-use-only (RUO) hexapeptide supplied at ≥99% purity (HPLC & MS verified). This selective GHSR-1a (ghrelin receptor) agonist is ideal for in-vitro GPCR signaling, ligand-binding, and analytical method-development workflows where sequence fidelity, documentation, and cold-chain integrity are essential.
Specifications
| Property | Details |
|---|---|
| Chemical Name | Pralmorelin (GHRP-2) |
| CAS Number | 158861-67-7 |
| PubChem CID | 6852372 |
| Molecular Formula | C45H55N9O6 |
| Molecular Weight | ≈ 817.99 g/mol |
| Sequence (3-letter) | D-Ala – D-2-Nal – Ala – Trp – D-Phe – Lys-NH2 |
| Synonyms | GHRP-2; KP-102 |
| Physical Appearance | White to off-white lyophilized powder |
| Container | 3 mL glass vial (10 mg net content) |
| Purity | ≥99% verified by HPLC & MS (batch COA via on-vial QR) |
| Solubility | Soluble in sterile water or neutral aqueous buffers; prepare fresh. If required by your SOP, 0.22 µm filter after reconstitution. |
| Intended Use | Laboratory research only (RUO). Not for human or animal use. |
Molecular Structure
View on PubChem (CID 6852372)
Key Features of Peptide Tech
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Potential Applications in Research
Strictly for in-vitro, cell-based, or biochemical experiments. No health, diagnostic, or therapeutic claims.
- GHSR-1a signaling assays — calcium flux (e.g., Fluo-4) or IP-One HTRF to quantify potency/efficacy and desensitization under serum-defined conditions.
- β-arrestin recruitment & receptor internalization (BRET/ELISA/confocal) to profile trafficking and potential biased-signaling signatures at GHSR-1a.
- Radioligand/competition binding in membranes or intact cells to determine affinity (Ki), association/dissociation rates, and rank-order versus other GHS agonists.
- Pathway cross-talk mapping (PLC/IP3/Ca2+ vs. ERK/Akt) using reporter panels and western blot readouts.
- Analytical method development (RP-HPLC/LC–MS/MS) for identity, stability, and recovery across buffers, temperatures, and freeze–thaw cycles.
Quality, Storage & Handling
Each lot is confirmed by HPLC (purity) and MS (identity); the QR on the vial links to the batch COA. Independent U.S. labs verify purity, quantity, and endotoxin.
- Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
- After reconstitution: Aliquot and store at ≤−20 °C (or −80 °C per SOP); avoid repeated freeze–thaw cycles.
- Reconstitution tips: Use sterile water or compatible buffer; gently invert to dissolve. If needed, a minimal 0.1% acetic acid pre-wet can aid dissolution before final dilution.
Shipping & Fulfillment
Ships in validated cold-chain packaging. In-stock orders placed before the daily cutoff ship the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included; international shipping available where permitted.
Compliance & RUO Disclaimer
For laboratory research only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, ingestion, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines.
FAQs
- Is GHRP-2 the same as Pralmorelin?
- Yes — Pralmorelin is the INN for GHRP-2 (CAS 158861-67-7; formula C45H55N9O6). See PubChem CID 6852372 for reference.
- What purity do you provide?
- Each 10 mg vial is ≥99% by HPLC with MS identity confirmation; third-party testing is performed on every lot (COA via on-vial QR).
- How should I reconstitute it?
- Use sterile water or a compatible buffer; gently swirl until fully dissolved. If your protocol requires sterility, pass through a 0.22 µm filter and aliquot to avoid repeat freeze–thaw.
- How does this differ from GHRP-6?
- GHRP-6 includes His and a different motif; GHRP-2 is D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2. Validate performance in your specific assay format.
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