Specifications
| Property | Details |
|---|---|
| CAS Number | 137525-51-0 |
| Chemical Name | Stable gastric pentadecapeptide BPC-157 |
| PubChem CID | PubChem CID 9941957 |
| Molecular Formula | C62H98N16O22 |
| Molecular Weight | ≈ 1419.5 g/mol (free base) |
| Physical Appearance | White to off-white lyophilized powder |
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (GEPPPGKPADDAGLV) |
| Container | 3 mL glass vial (5 mg net content) |
| Purity | ≥99% verified by HPLC & MS |
| Solubility | Soluble in sterile water or saline/aqueous buffer; optimize pH/ionic strength for your assay and filter-sterilize if required |
Molecular Structure
Key Features of Peptide Tech
- Same-Day Shipping (Mon–Fri, on in-stock items)
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Potential Applications in Research
Strictly in-vitro/cellular/biochemical contexts; no clinical or animal claims.
- Endothelial tube-formation assays (e.g., HUVEC models) to evaluate angiogenesis-related readouts and pathway activation under controlled conditions. See: Hsieh et al., 2017; Huang et al., 2015.
- Cell migration & adhesion workflows (scratch/transwell) in tendon/mesenchymal or endothelial cultures to quantify motility and matrix interaction metrics. See: Chang et al., 2011.
- Signal-transduction mapping (e.g., VEGFR2–Akt–eNOS axis) using reporter assays, immunoblotting, or high-content imaging under standardized media/ligand conditions. See: Hsieh et al., 2017.
- Analytical method development for peptide detection/quantitation (LC-MS/MS; metabolic stability, matrix effects, reference controls). See: Cox et al., 2017.
- Stability/handling studies evaluating solvent choice, temperature, and freeze–thaw cycling impacts on assay performance and recovery (general peptide best practices; reference your lab SOPs).
Citations
- Hsieh, Ming-Jer, et al. “Therapeutic Potential of Pro-Angiogenic BPC157 Is Associated with VEGFR2 Activation and Up-Regulation.” Journal of Molecular Medicine, vol. 95, no. 3, 2017. https://pubmed.ncbi.nlm.nih.gov/27847966/
- Huang, Tzu-Hua, et al. “Body Protective Compound-157 Enhances Alkali-Burn Wound Healing and Reduces Corneal Neovascularization.” PLOS ONE, 2015. https://pmc.ncbi.nlm.nih.gov/articles/PMC4425239/
- Chang, Chung-Hsun, et al. “The Promoting Effect of Pentadecapeptide BPC 157 on Tendon Healing Involves Tendon Outgrowth, Cell Survival, and Cell Migration.” Journal of Applied Physiology, vol. 110, no. 3, 2011, pp. 774–780. https://journals.physiology.org/doi/10.1152/japplphysiol.00945.2010
- Cox, Holly D., et al. “Detection and In Vitro Metabolism of the Confiscated Peptides BPC 157 and MGF R23H.” Drug Testing and Analysis, 2017. https://pubmed.ncbi.nlm.nih.gov/28035768/
- PubChem Compound Summary for CID 9941957: BPC-157. https://pubchem.ncbi.nlm.nih.gov/compound/9941957
Quality, Storage & Handling
Each lot is confirmed by HPLC (purity) and MS (identity), with QR-linked batch documentation. Third-party U.S. labs verify purity, quantity, and endotoxin.
- Storage (lyophilized): −20 °C (long term) or 2–8 °C (short term), desiccated and protected from light.
- After reconstitution: Aliquot and store at ≤−20 °C or −80 °C per SOP; avoid repeated freeze–thaw.
- Handling: Use sterile technique; select solvent/buffer compatible with your assay; gently invert/sonicate if needed to fully dissolve.
Shipping & Fulfillment
Ships with validated cold-chain packaging. In-stock orders placed before the daily cutoff dispatch the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email order updates are included; international service is available where permitted.
Compliance & RUO Disclaimer
For laboratory research use only. Not for human or animal use, ingestion, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines. COAs are available via QR or upon request.
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([PubChem][1], [MilliporeSigma][2], [PubMed][3], [Physiology Journals][4])
[1]: https://pubchem.ncbi.nlm.nih.gov/compound/Bpc-157?utm_source=chatgpt.com “Bpc-157 | C62H98N16O22 | CID 9941957”[2]: https://www.sigmaaldrich.com/US/en/search/137525-51-0?focus=products&page=1&perpage=30&sort=relevance&srsltid=AfmBOoqTrbJq2okAQdhZZ7NTmzK1qL8BfNM6RXdzHzWQeJ8vrQrpMCoI&term=137525-51-0&type=cas_number&utm_source=chatgpt.com “CAS 137525-51-0”
[3]: https://pubmed.ncbi.nlm.nih.gov/27847966/?utm_source=chatgpt.com “Therapeutic potential of pro-angiogenic BPC157 is …”
[4]: https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00945.2010?utm_source=chatgpt.com “The promoting effect of pentadecapeptide BPC 157 on tendon …”




















