GHRP-2 5 mg (Pralmorelin) from Peptide Tech is a premium, lyophilized research-use-only (RUO) hexapeptide supplied at ≥99% purity (HPLC & MS verified). A selective GHSR1a (ghrelin receptor) agonist, GHRP-2 is widely used in in-vitro GPCR signaling, calcium-mobilization, ligand-binding, and analytical method development where sequence fidelity and cold-chain integrity matter.
Specifications
| Property | Details |
|---|---|
| CAS Number | 158861-67-7 |
| Chemical Name | D-Alanyl-3-(2-naphthyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide (Pralmorelin; GHRP-2) |
| PubChem CID | 6918245 |
| Molecular Formula | C45H55N9O6 |
| Molecular Weight | ~817.98 g/mol |
| Physical Appearance | White to off-white lyophilized powder |
| Sequence | D-Ala–D-2-Nal–Ala–Trp–D-Phe–Lys-NH2 |
| Container | 3 mL glass vial (5 mg net content) |
| Purity | ≥99% verified by HPLC & MS (lot COA via QR) |
| Solubility | Soluble in sterile water or compatible aqueous buffer; optimize pH/ionic strength for your assay; filter-sterilize if required |
| Intended Use | Laboratory research only (RUO). Not for human or animal use. |
Molecular Structure
Key Features of Peptide Tech
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Potential Applications in Research
Strictly in-vitro, cell-based, or biochemical experiments. No health claims or clinical/veterinary use.
- GHSR1a calcium-mobilization assays (e.g., CHO/HEK293 models) using fluorescent indicators or GECIs to quantify agonist potency and receptor desensitization.
- β-arrestin recruitment & receptor internalization (BRET/ELISA/confocal) to study trafficking and biased signaling at GHSR1a.
- Radioligand/competition binding to determine affinity/kinetics and rank-order potency across GHSR ligands in membrane preparations.
- Pathway mapping (PLC–IP3–Ca2+, ERK/MAPK, Akt) via reporter assays and immunoblotting under standardized conditions.
- Analytical method development (LC–MS/MS) for detection/quantitation of GHRP-2 and related GHSR agonists in lab matrices.
Quality, Storage & Handling
Every lot is confirmed by HPLC (purity) and MS (identity); batch-level COA is accessible via on-vial QR. Independent U.S. labs verify purity, quantity, and endotoxin.
- Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
- After reconstitution: Aliquot and store at ≤−20 °C (or −80 °C per SOP); avoid repeated freeze–thaw.
- Reconstitution tips: Use sterile water or suitable buffer; gentle inversion/brief sonication can aid dissolution; filter-sterilize if required.
Shipping & Fulfillment
Ships with validated cold-chain packaging. In-stock orders placed before the daily cutoff ship the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included; international shipping available where permitted.
Compliance & RUO Disclaimer
For laboratory research only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, clinical, veterinary, or diagnostic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines. COAs available on request or via QR.
FAQs
- Is this for human or veterinary use?
- No. This product is sold strictly as RUO and must not be used in humans or animals.
- What purity do you provide?
- Each 5 mg vial is ≥99% by HPLC with MS identity confirmation; third-party testing is performed on every lot (see COA via QR).
- How should I reconstitute it?
- Use sterile water or compatible buffer; gently invert until dissolved. If your protocol requires, 0.22 µm filter-sterilize and aliquot to avoid repeat freeze–thaw.
- What in-vitro assays is GHRP-2 commonly used in?
- Typical RUO uses include GHSR1a Ca2+ signaling, β-arrestin/internalization workflows, radioligand binding, and LC–MS/MS method development.
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