PT-141 (Bremelanotide) 20 mg from Peptide Tech is a premium, lyophilized research-use-only (RUO) peptide supplied at ≥99% purity (HPLC & MS verified). This cyclic heptapeptide melanocortin-receptor agonist is ideal for in-vitro receptor pharmacology, cAMP signaling, and ligand-binding workflows where sequence fidelity and batch traceability are critical.

Specifications

Property	Details
CAS Number	189691-06-3
Chemical Name	Bremelanotide (PT-141)
PubChem CID	9941379
Molecular Formula	C₅₀H₆₈N₁₄O₁₀
Molecular Weight	≈ 1025.2 g/mol
Physical Appearance	White to off-white lyophilized powder
Sequence	Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH (lactam bridge Asp↔Lys)
Container	3 mL glass vial (20 mg net content)
Purity	≥99% verified by HPLC & MS (lot COA via on-vial QR)
Solubility	Soluble in sterile water or compatible aqueous buffer; prepare fresh and protect from light; filter-sterilize if required by your SOP
Intended Use	Laboratory research only (RUO). Not for human or animal use.

Molecular Structure

Key Features of Peptide Tech

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3rd-Party U.S. Lab Testing — purity, quantity, endotoxin
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Potential Applications in Research

Strictly for in-vitro, cellular, or biochemical experiments. No health, diagnostic, or therapeutic claims.

Melanocortin receptor signaling (MC1R/MC3R/MC4R) using cAMP reporters (e.g., CRE-luc, HTRF cAMP) to quantify potency/efficacy and desensitization kinetics.
β-arrestin recruitment & receptor internalization (BRET/ELISA/confocal) to profile trafficking and biased-signaling signatures across melanocortin subtypes.
Radioligand/competition binding in membrane preparations or intact cells to determine affinity (K_i), association/dissociation rates, and rank-order potency vs. related analogs.
Melanogenesis pathway readouts in melanocyte cultures (e.g., tyrosinase activity, melanin content) under controlled media/light conditions.
Analytical method development (RP-HPLC/LC–MS/MS) for identity, stability, and recovery across buffers and temperatures.

Quality, Storage & Handling

Every lot is confirmed by HPLC (purity) and MS (identity); batch COA is accessible via on-vial QR. Independent U.S. labs verify purity, quantity, and endotoxin.

Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
After reconstitution: Aliquot and store at ≤−20 °C (or −80 °C per SOP); avoid repeated freeze–thaw.
Reconstitution tips: Use sterile water or suitable buffer; gently swirl to dissolve; 0.22 µm filter only if required by your assay.

Shipping & Fulfillment

Ships with validated cold-chain packaging. In-stock orders placed before the daily cutoff ship the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included; international shipping available where permitted.

Compliance & RUO Disclaimer

For laboratory research only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, ingestion, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines.

FAQs

Is this intended for human or veterinary use?: No. This product is sold strictly as RUO and must not be used in humans or animals.
What purity do you provide?: Each 20 mg vial is ≥99% by HPLC with MS identity confirmation; third-party testing is performed on every lot (see COA via QR).
How should I reconstitute it?: Use sterile water or a compatible buffer; gently invert until fully dissolved. If your protocol requires sterility, pass through a 0.22 µm filter and aliquot to avoid repeat freeze–thaw.
Which in-vitro assays is PT-141 commonly used in?: Typical RUO uses include melanocortin receptor cAMP assays, β-arrestin/internalization workflows, radioligand binding, and LC–MS/MS method development.