A research-grade reta-class peptide analog (triple agonist at GLP-1R, GIPR, and GCGR) — from Peptide Tech is a premium, lyophilized research-use-only (RUO) reagent supplied at ≥99% purity (HPLC & MS verified). Optimized for in-vitro GPCR pharmacology (cAMP, β-arrestin), ligand-binding, and analytical method development where sequence fidelity, documentation, and cold-chain integrity are essential.

Specifications

Property	Details
Product Type	Synthetic peptide analog (reta class; tri-agonist)
Synonyms	Reta analog; GLP-1/GIP/Glucagon tri-agonist
CAS / Registry	Not assigned for this research analog; see lot COA
PubChem	Not applicable for this analog; see lot COA for identifiers
Molecular Formula / MW	Sequence- and salt-dependent (reported on COA)
Sequence	Proprietary retatrutide-class sequence; disclosed on lot COA
Counter-ion	Typically acetate (confirm on COA)
Appearance	White to off-white lyophilized powder
Container	3 mL glass vial (5 mg net content)
Purity	≥99% by HPLC; identity by MS (batch COA via on-vial QR)
Solubility	Soluble in sterile water or neutral aqueous buffers; gentle inversion/brief sonication may aid dissolution. If required by your SOP, 0.22 µm filter after reconstitution.
Intended Use	Laboratory research only (RUO). Not for human or animal use.

Molecular Structure

This RUO analog belongs to the GLP-3 class. Exact primary sequence, any lipidation/side-chain modifications, and calculated formula/MW are provided on the lot-matched COA (access via on-vial QR). A single canonical 2D rendering is not shown here because minor variant differences may exist lot-to-lot.

Key Features of Peptide Tech

Same-Day Shipping (Mon–Fri, on in-stock items)
GMP-Aligned Lyophilized Peptides
USA Made
24/7 Support
Price Match Guarantee
Batch Tracking with QR Code Verification
Third-Party U.S. Lab Testing — purity, quantity, endotoxin
Cold-Chain Shipping — Always (no paid upgrade)
Worldwide Shipping
All Major Payments Accepted
Text & Email Order Updates
2-Day FedEx/UPS Shipping Standard
Cheapest Overnight Rates
Largest Variety of Peptides & Bioregulators

Potential Applications in Research

Strictly for in-vitro, cellular, or biochemical experiments. No health, diagnostic, or therapeutic claims.

GPCR cAMP accumulation assays at GLP-1R, GIPR, and GCGR (e.g., CRE-luc/HTRF cAMP) to quantify potency/efficacy and desensitization.
β-arrestin recruitment & receptor internalization (BRET/ELISA/confocal) to profile trafficking and potential biased signaling across the three receptors.
Radioligand/competition binding in membranes or intact cells to rank affinities and association/dissociation kinetics versus related incretin/glucagon analogs.
Pathway mapping (Gs→AC→cAMP→PKA/CREB; cross-talk to ERK/Akt) using reporter panels and immunoblotting under serum-defined conditions.
Analytical method development (RP-HPLC/LC–MS/MS) for identity, recovery, stability, and forced-degradation studies in buffered matrices.

Quality, Storage & Handling

Every lot is confirmed by HPLC (purity) and MS (identity); batch COA is accessible via on-vial QR. Independent U.S. labs verify purity, quantity, and endotoxin.

Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
After reconstitution: Aliquot and store at ≤−20 °C (or −80 °C per SOP); avoid repeated freeze–thaw cycles.
Reconstitution tips: Use sterile water or compatible buffer; gently invert to dissolve. If needed, a minimal amount of 0.1% acetic acid can aid solubilization before final dilution.

Shipping & Fulfillment

Ships in validated cold-chain packaging. In-stock orders placed before the daily cutoff ship the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included; international shipping available where permitted.

Compliance & RUO Disclaimer

For laboratory research only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, ingestion, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines.

FAQs

Is this the same as clinical retatrutide?: No. This is a research-only analog configured for in-vitro work. It is not intended for human or animal use.
What purity do you provide?: Each 5 mg vial is ≥99% by HPLC with MS identity confirmation; third-party testing is performed on every lot (see COA via QR).
Can you share the exact sequence?: The lot-specific primary sequence, any side-chain/lipidation details, and calculated formula/MW are disclosed on the COA linked by the on-vial QR.
Which in-vitro assays is this commonly used in?: Typical RUO applications include GLP-1R/GIPR/GCGR cAMP assays, β-arrestin/internalization workflows, radioligand binding, and LC–MS method development.