Gonadorelin (GnRH) 2 mg from Peptide Tech is a premium, lyophilized research-use-only (RUO) decapeptide supplied at ≥99% purity (HPLC & MS verified). This peptide—also known as luteinizing hormone–releasing hormone (LHRH)—is widely used in in-vitro receptor-binding, calcium-mobilization, and pathway-mapping studies where sequence fidelity and batch traceability are essential.

Specifications

Property	Details
CAS Number	33515-09-2 (free base)
Chemical Name	PyroGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH₂ (Gonadorelin; GnRH; LHRH)
PubChem CID	638793
Molecular Formula	C₅₅H₇₅N₁₇O₁₃
Molecular Weight	≈ 1182.31 g/mol
Physical Appearance	White to off-white lyophilized powder
Sequence	pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH₂
Container	3 mL glass vial (2 mg net content)
Purity	≥99% verified by HPLC & MS (lot COA via on-vial QR)
Solubility	Soluble in sterile water or compatible aqueous buffer; optimize pH/ionic strength for your assay and filter-sterilize if required
Intended Use	Laboratory research only (RUO). Not for human or animal use.

Molecular Structure

Key Features of Peptide Tech

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Potential Applications in Research

Strictly in-vitro, cell-based, or biochemical experiments. No health claims or clinical/veterinary use.

GnRH receptor (GNRHR) calcium-mobilization assays in receptor-positive cells (e.g., CHO/HEK293 lines) to map G_q/PLC–IP₃–Ca²⁺ signaling and oscillation patterns.
Radioligand/competition binding with iodinated GnRH analogs to determine affinity/kinetics and rank-order potency across ligands.
Pathway mapping (PLC/IP₃, PKC, and ERK/MAPK) via reporter assays, Western blotting, and high-content imaging in standardized media conditions.
Receptor internalization & β-arrestin recruitment using confocal/BRET/ELISA readouts to study desensitization and trafficking phenotypes.
Analytical method development (RP-HPLC and LC–MS/MS) for peptide detection/quantitation, matrix effects, and stability profiling.

Quality, Storage & Handling

Every lot is confirmed by HPLC (purity) and MS (identity); batch COA is accessible via on-vial QR. Independent U.S. labs verify purity, quantity, and endotoxin.

Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
After reconstitution: Aliquot and store at ≤−20 °C (or −80 °C per SOP); avoid repeated freeze–thaw.
Reconstitution tips: Use sterile water or suitable buffer; gentle inversion/brief sonication can aid dissolution; filter-sterilize if required.

Shipping & Fulfillment

Ships with validated cold-chain packaging. In-stock orders placed before the daily cutoff ship the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included; international shipping available where permitted.

Compliance & RUO Disclaimer

For laboratory research only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, clinical, veterinary, or diagnostic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines. COAs available upon request or via QR.

FAQs

Is this for human or veterinary use?: No. This product is sold strictly as RUO and must not be used in humans or animals.
What purity do you provide?: Each 2 mg vial is ≥99% by HPLC with MS identity confirmation; third-party testing is performed on every lot (see COA via QR).
How should I reconstitute it?: Use sterile water or a compatible buffer; gently invert until dissolved. If your protocol requires, 0.22 µm filter-sterilize and aliquot to avoid repeat freeze–thaw.
What in-vitro assays is Gonadorelin commonly used in?: Typical RUO uses include GNRHR Ca²⁺ signaling, radioligand binding, ERK/MAPK pathway studies, β-arrestin/internalization workflows, and LC–MS/MS method development.